Analysis of HIV-1 FTSJ3-dependent 2'-O-methylation
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https://www.ncbi.nlm.nih.gov/sra/ERP111746
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HIV-1 RNA was extracted from viral particles and analyzed by RiboMethSeq. Analysis was performed for WT HIV-1 RNA, corresponding in vitro transcripts, HIV-1 RNA produced in the cells with siRNA antiFTSJJ3 and anti-TRBP and for CRISPR/Cas9 deleted FTSJ3. Results show the existence of internal methylation sites in HIV-1 RNA, many of these sites are FTSJ3-dependent
创建时间:
2019-01-25



