NOTCH3 binds DLL1
收藏reactome.org2025-01-09 收录
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Based on a study with mouse proteins, NOTCH3 receptor binds to DLL1 ligand (Shimizu et al. 2000). The interaction of DLL1 and NOTCH3 is implicated in functional differentiation of activated CD4+ T lymphocytes into type 1 helper T cells (Th1) (Maekawa et al. 2003). The effect of Fringe-mediated modification of NOTCH3 on its interaction with DLL1 is poorly studied (Hou et al. 2012).
基于对小鼠蛋白的研究,NOTCH3受体与DLL1配体(Shimizu等人,2000年)发生结合。DLL1与NOTCH3的相互作用与激活的CD4+ T淋巴细胞向1型辅助T细胞(Th1)的功能分化密切相关(Maekawa等人,2003年)。关于Fringe介导的NOTCH3修饰对其与DLL1相互作用的影响研究尚显不足(Hou等人,2012年)
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