Meta-regression analysis between each continuous variable among the studies (only treatment- naïve patients were included) and the effect (log odds ratio) of IL28B polymorphisms on inflammation activity.

*Positive (negative) slope values indicate that the proportions of patients with the rs12979860 CC genotype with severe inflammation activity are increasing (decreasing) as the values of each contentious variable (proportions of genotype 1 or 4 virus, male, or each race) is increasing.†We could not perform meta-regression analyses for these outcomes because only caucasian patients were included in all 3 studies included in this analysis.