Lewis Acid-Catalyzed Diastereoselective Hydroarylation of Benzylidene Malonic Esters
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https://figshare.com/articles/dataset/Lewis_Acid_Catalyzed_Diastereoselective_Hydroarylation_of_Benzylidene_Malonic_Esters/2848771
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资源简介:
Herein we report that simple Lewis acids catalyze the hydroarylation of benzylidene malonates with phenols. Ultimately, 3,4-disubstituted dihydrocoumarins are obtained via a hydroarylation−lactonization sequence. Moreover, the dihydrocoumarins are formed with a high degree of diastereoselectivity favoring the trans stereoisomer.
创建时间:
2016-02-26



