Crystal structure of Streptococcus pyogenes endo-beta-N-acetylglucosaminidase (EndoS2) with high-mannose glycan

Crystal structure of Streptococcus pyogenes endo-beta-N-acetylglucosaminidase (EndoS2) with high-mannose glycan Descriptor: CALCIUM ION, Endo-beta-N-acetylglucosaminidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Klontz, E.H, Trastoy, B, Orwenyo, J, Wang, L.X, Guerin, M.E, Sundberg, E.J. Deposit date: 2018-09-05 Release date: 2019-02-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Molecular Basis of Broad SpectrumN-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2. ACS Cent Sci, 5, 2019

化脓性链球菌（Streptococcus pyogenes）内切β-N-乙酰葡糖胺糖苷酶（Endo-beta-N-acetylglucosaminidase，简称EndoS2）结合高甘露糖型聚糖（high-mannose glycan）的晶体结构
描述项：钙离子（CALCIUM ION）、内切β-N-乙酰葡糖胺糖苷酶（Endo-beta-N-acetylglucosaminidase）、α-D-吡喃甘露糖-(1→2)-α-D-吡喃甘露糖-(1→2)-α-D-吡喃甘露糖-(1→3)-[α-D-吡喃甘露糖-(1→3)-[α-D-吡喃甘露糖-(1→6)]α-D-吡喃甘露糖-(1→6)]β-D-吡喃甘露糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖……
作者：Klontz, E.H、Trastoy, B、Orwenyo, J、Wang, L.X、Guerin, M.E、Sundberg, E.J
存档日期：2018年9月5日
发布日期：2019年2月6日
最后修改日期：2023年10月11日
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.5 Å
引用文献：《内切糖苷酶S2介导治疗性IgG单克隆抗体的广谱N聚糖特异性与加工过程的分子基础》，ACS Central Science, 5, 2019