scRNA-seq of AAV-scramble or AAV-shBicd2 infected mice livers under Con A-induced acute autoimmune hepatitis

To explore the effect of Bicd2 in Con A-induced acute autoimmune hepatitis, we conducted single cell RNA sequencing of AAV-scramble or AAV-shBicd2 infected mice livers in response to Con A injection. We infected 4w wild-type C57BL/6J mice with AAV-scramble or AAV-shBicd2. After 3 weeks, mice were injected with 15mg/kg Con A i.v. and 6 hours later livers were collected to perform single cell RNA sequecing.