List of predicted transcription factor binding site motifs within proximal tubule anchor gene set promoters.

CLOVER analysis report of transcription factor binding site (TFBS) motif from JASPAR motif library (TF Motif), transcription factor family (TF class), anchor gene promoter sequence analysis used to predict TF motif (Promoter seq. set) Core  =  Mouse RefSeq gene promoter sequences at -500/+200bp from transcription start site; ECR  =  evolutionarily conserved regions within RefSeq promoter sequence. Count and list of individual anchor genes (# genes and Target Genes respectively) with predicted TFBS motifs based on p-value (p-value). Published observations of renal defects based on transcription factor genetic manipulation studies (Renal defect), GUDMAP-based ISH kidney expression annotation (Expression in developing kidney), and GUDMAP and/or literature evidence for expression/association with early proximal tubule (EPT expression). RI  =  renal interstitium (including medullary (MI) and cortical interstitial (CI) compartments); MM  =  metanephric mesenchyme; CM  =  cap mesenchyme; RV  =  renal vesicle; SSB  =  S-shaped body; PT  =  proximal tubule; LOH  =  loop of Henle; DT  =  distal tubule; vasc  =  vasculature; UT  =  ureteric tip; UB  =  ureteric bud. Early tubule may include RV and/or SSB stage nephrons.