Additional file 8 of The autophagy interaction network of the aging model Podospora anserina

Hybrid PPI network. This file gives the underlying data of Fig. 2. In contrast to Additional file 1, this file contains all interactions, proteins and homologous relations of the autophagy hybrid PPI network, comprising both reference PPI networks, the predicted PPI network and the homology network which connects all three PPI networks. As for Additional file 1, two edge types can be distinguished. First, edges indicating an interaction, where the source and the target node correspond to proteins in the same species. Second, edges indicating a homologous relation where the source protein belongs to P. anserina and the target protein to yeast or human. UniProt accession numbers were used as identifiers for proteins of yeast and human. The identifiers for P. anserina proteins were adopted from the P. anserina genome database. Species were distinguished by their NCBI taxonomy IDs: Homo sapiens (9606), Podospora anserina (5145) and Saccharomyces cerevisiae S288c (559292). (XLS 105 kb)