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Hdac6 regulates Tip60-p400 function in stem cells (gene expression). Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA181060
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To identify the functional role of Hdac6 in embryonic stem cells, we examined gene expression changes in mouse ES cells upon Tip60, Hdac6 and double knockdown. Overall design: Two biological replicates each for control (GFP), Tip60, Hdac6 and double KD in E14 mouse ESCs. Lentiviral-based shRNA was used and gene expression changes were determined 3 days after KD. The global gene expression profiles of Tip60, Hdac6 and double KD were compared to control KD cells.
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2012-11-09
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