Additional file 1 of MicroRNA-Transcription factor regulatory networks in the early strobilar development of Echinococcus granulosus protoscoleces

Additional file 1: Table S1. List of Echinococcus granulosus Transcription factors with differentially expressed genes in early stages of strobilar development. Table S2. List of predicted targets derived from miRanda, PITA, and RNA22 and their comparison with 818 differentially expresssed genes and 41 differentially expressed transcription factors. Table S3. The summary of gene enrichment data obtained from KEGG database for predicted targets of selected differentially expressed miRNAs. Table S4. Prediction of protein?protein interaction network for six differentially expressed TFs by using the Search Tool for Recurring Instances of Neighboring Genes (STRING). Table S5. Comparison of the in vivo, in vitro and the RNA-seq data of the selected differentially expressed TFs and their related miRNAs. Table S6. Calculation of the Betweenness, Degree and Closeness centrality of the predicted network by using the cytoHubba (version 0.1). Table S7. List of Echinococcus granulosus differentially expressed genes in early stages of strobilar development according to Debarba et. al 2020. Table S8. List of Echinococcus granulosus miRNAs with differentially expressed genes in early stages of strobilar development according to Bai et. al 2020. Table S9. List of 396 Echinococcus granulosus Transcription factors and related DNA-binding domains/transcription factors families according to AnimalTFDB 3.0 database (394 unique TFs). Table S10. Sequences of forward and reverse primers of eight differentially expressed transcription factors and references genes used in qPCR validation.