Binding and endopeptidase inhibition characteristics of BoNT/A LC specific scFv mAbs.
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1 Affinities measured for yeast-displayed scFv using flow cytometry and the indicated antigen. 2 Inhibition of substrate cleavage determined by SDS-PAGE and FRET (Fig 2). 3 Epitope recognized by scFv arbitrarily grouped by number depending on competition for the same binding site illustrated in Fig 2. 4 NB; no binding of the antigen was detected at 200nM. Binding and endopeptidase inhibition characteristics of BoNT/A LC specific scFv mAbs.
创建时间:
2015-08-14



