Association between SLC6A2 SNPs and ADHD cognitive dimensions in the total sample.

WISC = Wechsler Intelligence Scale, SOPT = Self-Ordered Pointing Task, FW = Finger Windows, CPT = Continuous Performance Test, SE = standard error, RT = reaction time, ISI = inter-stimulus interval, WCST = Wisconsin Card Sorting Test, TOL = Tower of London.Standard scores were used for all WCST and TOL measures, and T-scores were used for CPT measures (excl. overall index).Three major haplotype blocks in SLC6A2 are depicted above: Block 1 (rs1362621, rs2397771, rs168924, rs2242446, rs3785143, rs192303, rs41154); Block 2 (rs36017, rs10521329, rs3785155, rs5564, rs11568324, rs2279805, rs8047672, rs5569, rs998424, rs36009); and Block 3 (rs1800887, rs2242447, rs15534).Significance (p) value ranges are depicted as follows: For OVER-TRANSMISSION of alleles = +4 (≤0.00001), +3 (0.0001–0.0009), +2 (0.001–0.009), and +1 (0.01–0.049).For UNDER-TRANSMISSION of alleles = −4 (≤0.00001), −3 (0.0001–0.0009), −2 (0.001–0.009) and −1 (0.01–0.049).