Expression data of wild-type and perforin-knockout CAR-T cell
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE130929
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资源简介：
Murine chimeric antigen receptor transduced T cells (CAR-T cells) deficient in perforin recapitulate hemophagocytic lymphohistiocytosis (HLH)-like toxicities occuring in human CAR-T recipients. We used microarray to describe gene expression profiles of wild-type and perforin-deficient CAR-T cells. RNA was extracted from murine wild-type and perforin-deficient CD8+ CAR-T cells, before and after CAR-mediated in vitro activation of T cells with cognate-antigen-positive leukemia, followed by hybridization on Affymetrix array.
创建时间：
2020-10-07
