Synthesis of the Reported Pyranonaphthoquinone Structure of the Indoleamine-2,3-dioxygenase Inhibitor Annulin B by Regioselective Diels–Alder Reaction
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https://figshare.com/articles/dataset/Synthesis_of_the_Reported_Pyranonaphthoquinone_Structure_of_the_Indoleamine-2_3-dioxygenase_Inhibitor_Annulin_B_by_Regioselective_Diels_Alder_Reaction/3753207
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资源简介：
Annulin
B, isolated from the marine hydroid isolated from Garveia
annulata, is a potent inhibitor of the tryptophan
catabolizing enzyme indoleamine-2,3-dioxygenase (IDO). A synthesis
of the reported pyranonaphthoquinone structure is described, in which
the key step is a regioselective Diels–Alder reaction between
a pyranobenzoquinone dienophile and a silyl ketene acetal diene.
创建时间：
2016-08-29
