Ppp4c

ENCODES a protein that exhibits lamin binding; phosphatase activity; protein-containing complex binding; INVOLVED IN cellular response to interleukin-1; dephosphorylation; negative regulation of protein phosphorylation; PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 16p11.2 deletion syndrome, 593-kb (ortholog); FOUND IN nucleus; chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride

编码一种具有层粘连蛋白结合、磷酸酶活性、含蛋白质复合物结合特性的蛋白质；参与细胞对白细胞介素-1的反应、脱磷酸化、蛋白质磷酸化的负调控；参与突变型着丝粒性毛细血管扩张（ATM）信号通路；与自闭症谱系障碍（同源）、自闭症（同源）、16p11.2染色体缺失综合征（593-kb，同源）相关；存在于细胞核、染色质（同源）、细胞质（同源）中；与17β-雌二醇、2,3,7,8-四氯二苯并-对-二恶英、氯化铵相互作用。