Crystal structure of the second bromodomain (BD2) of human BRD2 bound to bromosporine
收藏Protein Data Bank Japan2023-10-18 更新2026-03-28 收录
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Crystal structure of the second bromodomain (BD2) of human BRD2 bound to bromosporine Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 2, Bromosporine, ... Authors: Karim, M.R, Bikowitz, M.J, Chan, A, Schonbrunn, E. Deposit date: 2020-12-23 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors. J.Med.Chem., 64, 2021
人类BRD2的第二个溴结构域（BD2）与溴孢菌素结合的晶体结构。描述组分：1,2-乙二醇、含溴结构域蛋白2（Bromodomain-containing protein 2）、溴孢菌素等。作者：Karim, M.R、Bikowitz, M.J、Chan, A、Schonbrunn, E.。沉积日期：2020-12-23，发布日期：2021-06-23，最后修改日期：2023-10-18。实验方法：X射线衍射（分辨率1.55埃）。引用文献：《二氢蝶啶酮与嘧啶并二氮杂卓酮类激酶抑制剂对BET溴结构域的差异化抑制作用》，J.Med.Chem., 64, 2021
创建时间：
2020-12-23
