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Otulin inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE180024
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资源简介:
Mice with epidermal keratinocyte specific knockout of OTULIN develop inflammatory skin disease. To study the inflammatory response we used Lexogen 3´mRNA sequencing to compare the gene expression profiles in the skin of OTULIN epidermis specific knockout and control mice. Skin samples were collected from 3-week old mice (OTULIN-KO, WT) for RNA extraction and subsequent 3´mRNA Sequencing.
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2021-10-21
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