Enantioselective Synthesis of Functionalized Pyrazoles by NHC-Catalyzed Reaction of Pyrazolones with α,β-Unsaturated Aldehydes
收藏Figshare2016-02-14 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Enantioselective_Synthesis_of_Functionalized_Pyrazoles_by_NHC_Catalyzed_Reaction_of_Pyrazolones_with_Unsaturated_Aldehydes/2184355
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资源简介:
The N-heterocyclic carbene (NHC)-organocatalyzed enantioselective annulation reaction of pyrazolones with α,β-unsaturated aldehydes proceeding via the chiral α,β-unsaturated acyl azolium intermediates under oxidative conditions is presented. The reaction afforded dihydropyranone-fused pyrazoles in moderate to good yields and good er values under operationally simple and base-free conditions.
创建时间:
2016-02-14



