Crystal structure of T252E-CYP199A4 in complex with 4-hydroxybenzoic acid. Crystal was initially co-crystallised with 4-methoxybenzoic acid and soaked with 4 mM hydrogen peroxide
收藏资源简介:
Crystal structure of T252E-CYP199A4 in complex with 4-hydroxybenzoic acid. Crystal was initially co-crystallised with 4-methoxybenzoic acid and soaked with 4 mM hydrogen peroxide Descriptor: CHLORIDE ION, Cytochrome P450, P-HYDROXYBENZOIC ACID, ... Authors: Lee, J.H.Z, Bruning, J.B, Bell, S.G. Deposit date: 2023-03-23 Release date: 2023-12-27 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.02 Å) Cite: An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase. Chemistry, 30, 2024
T252E突变型细胞色素P450(Cytochrome P450)CYP199A4与对羟基苯甲酸的复合物晶体结构。该晶体最初通过与对甲氧基苯甲酸共结晶获得,随后采用4 mM过氧化氢进行浸泡处理。标注项:氯离子、细胞色素P450、对羟基苯甲酸……作者:Lee, J.H.Z、Bruning, J.B、Bell, S.G。提交日期:2023年3月23日,发布日期:2023年12月27日,末次修改日期:2024年2月21日。解析方法:X射线衍射(分辨率2.02 Å)。引用文献:《工程化细胞色素P450过加氧酶的晶内反应》,《Chemistry》,第30卷,2024年。



