Isoforms showing a significantly differential response of transcript expression between wild-type and CPSF6 knockdown cells upon temperature changes.

Information about all 994 isoforms showing a significantly differential temperature response in DGE values (i.e., transcript abundance) between wild-type (WT) and CPSF6-depleted (KD) cells. Columns A-D depict the RefSeq IDs, gene symbols, as well as chromosome and strand information of the corresponding isoforms. Columns E-V contain the DGE values for each of the 3 technical replicates in control (WT) and CPSF6-depleted cells at all 3 tested temperatures, namely 32°C, 37°C, and 39°C. Columns W-Z depict the slope and intercept values of the linear regressions in wild-type and CPSF6-depleted cells, using temperature as independent and DGE values as dependent variables. Columns AA and AB depict corresponding P values and Benjamini–Hochberg corrected P values, respectively, obtained from our statistical test against the null hypothesis that the slopes describing the temperature dependency are identical in wild-type and CPSF6-depleted cells; see Materials and methods for details. (XLS)