Data accompanying the publication "Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments"

Research objective: determine whether pseudotopological models for DNA loop-extruding SMC complexes can explain roadblock bypass experiments (referring to https://doi.org/10.1016/j.celrep.2022.111491)Type of research: Single-molecule in vitro reconstitution of DNA loop extrusion using purified proteinsMethod of data collection: HiLO microscopyType of data: Images (.tif). Due to the large size of the raw data, pointers to the data location are included in this dataset

研究目标：明确用于DNA环挤出型SMC复合体（SMC complexes）的伪拓扑模型（pseudotopological models）能否解释路障绕过实验，相关研究详见https://doi.org/10.1016/j.celrep.2022.111491。研究类型：采用纯化蛋白开展DNA环挤出的单分子体外重构实验。数据采集方法：HiLO显微成像技术。数据类型：.tif格式图像。由于原始数据体量较大，本数据集仅包含指向数据存储位置的索引指针。