Expression profiles osteosarcoma cell lines and MET transformed osteoblast clones. Homo sapiens

We studied MET-transformed human primary osteoblasts (MET-HOBs), which we previously turned into osteosarcoma cells by LV driven over-expression of MET oncogene. We obtained distinct MET transformed HOB clones derived from independent events of transgene integration. To characterise the phenotype of the MET-HOB clones we used oligonucleotide microarrays. Expression profiles of MET-HOBs and osteosarcoma cell lines were compared. Overall design: To characterise the phenotype of the MET-HOB clones we used oligonucleotide microarrays