Stereocontrolled Synthesis of Left Halves of Halichondrins
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https://figshare.com/articles/dataset/Stereocontrolled_Synthesis_of_Left_Halves_of_Halichondrins/5315104
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A stereocontrolled synthesis of the left halves of halichondrins was reported. An intramolecular oxy-Michael reaction under basic conditions was used to construct the [6,6]-spiroketal in a stereocontrolled manner. With this approach, the left halves of halichondrins, homohalichondrins, and norhalichondrins were synthesized.
创建时间:
2017-08-16



