Supporting data for "Clinker: visualising fusion genes detected in RNA-seq data"
收藏DataCite Commons2025-05-26 更新2025-04-15 收录
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https://gigadb.org/dataset/100460
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资源简介:
Genomic profiling efforts have revealed a rich diversity of oncogenic fusion genes. While there are many methods for identifying fusion genes from RNA-seq data, visualising these transcripts and their supporting reads remains challenging. Clinker is a bioinformatics tool written in Python, R and Bpipe, that leverages the superTranscript method to visualise fusion genes (Davidson et al., 2017). We demonstrate the use of Clinker to obtain interpretable visualisations of the RNA-seq data that lead to fusion calls. In addition, we use Clinker to explore multiple fusion transcripts with novel breakpoints within the P2RY8-CRLF2 fusion gene in B-cell Acute Lymphoblastic Leukaemia (B-ALL).
提供机构:
GigaScience Database
创建时间:
2018-06-27



