Novel Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (PPAR) gamma-delta Agonists with High Potency and In-vivo Efficacy
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Novel Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (PPAR) gamma-delta Agonists with High Potency and In-vivo Efficacy Descriptor: 5-CHLORO-2-METHOXY-N-[2-[4-[(5-PROPAN-2-YL-1,3,4-THIADIAZOL-2-YL)SULFAMOYL]PHENYL]ETHYL]BENZAMIDE, PENTAETHYLENE GLYCOL, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA Authors: Marquette, J.-P, Mathieu, M. Deposit date: 2010-11-18 Release date: 2011-02-23 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (Ppar) Gamma / Delta Agonists with High Potency and in-Vivo Efficacy Chemmedchem, 6, 2011
新型磺酰噻二唑类化合物：以罕见结合模式作为部分双重过氧化物酶体增殖物激活受体γ/δ（Peroxisome Proliferator-Activated Receptor, PPAR）激动剂，兼具高效力与体内药效
描述项：5-氯-2-甲氧基-N-[2-[4-[(5-异丙基-1,3,4-噻二唑-2-基)氨磺酰基]苯基]乙基]苯甲酰胺、五甘醇、过氧化物酶体增殖物激活受体δ（PPARδ）
作者：Marquette, J.-P、Mathieu, M.
提交日期：2010-11-18
发布日期：2011-02-23
最后修改日期：2024-05-01
实验方法：X射线衍射（2.3埃）
引用文献：《具有罕见结合模式的部分双重过氧化物酶体增殖物激活受体γ/δ激动剂：兼具高效力与体内药效》，Chemmedchem，第6卷，2011年
创建时间：
2010-11-18
