Genotyping and Clinical Data for CDK8 Polymorphisms in Bladder Cancer Case-Control Study

This dataset contains two Excel files from a study investigating CDK8 gene polymorphisms in bladder cancer among Chinese Han population:1. SNP_Genotyping_Data.xlsx- Genotyping results for CDK8 polymorphisms (rs17083838 and rs7992670)- Data from 271 bladder cancer patients and 381 healthy controls from Chinese Han population- Variables include: sample ID, genotypes,age,gender,smoking status,age group,group (case/control)- Genotyping method:RFLP-PCR2. Clinical_Information.xlsx- Clinical and demographic data for bladder cancer patients- Variables include: sample ID, age, age group (young/elderly), gender (male/female), smoking status (smoker/nonsmoker), 5-year survival outcome (alive/dead), 5-year survival time (months), relapse status (yes/no), time to relapse (months), tumor stage (MIBC/NMIBC), tumor grade (High/Low), clinical stage (I-IV), metastasis status (yes/no)- Follow-up period: [2015-2020]- Treatment information and outcomesStudy period:2024Institution: Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan UniversityStatistical analyses performed include:- Hardy-Weinberg equilibrium testing- Association analysis between SNPs and cancer risk- Survival analysis using Kaplan-Meier method- Cox regression for prognostic analysisNote: All data has been anonymized to protect patient privacy.