Primary lung fibroblasts treated with hedgehog agonist, purmorphamine

ChEBI2016-07-03 更新2026-07-12 收录

Hedgehog信号通路

肺成纤维细胞

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Primary lung fibroblasts treated with hedgehog agonist, purmorphamine

创建时间：

2016-07-03

RNA-seq of MRC5

基因表达分析

肺成纤维细胞

We performed bulk RNA sequencing on the MRC5 human lung fibroblasts in an aim to identify the differential expression genes between groups with TGF-beta treatment and CD147 knockdown.

NIAID Data Ecosystem160

MRTF/SRF link the cytoskeleton and hedgehog pathway in drug-resistant basal cell carcinomas

化疗耐药机制

Hedgehog信号通路

We use multi-dimensional genomic analysis using mouse resistant BCCs to identify a non-canonical hedgehog activation pathway driven by the transcription factor, serum response factor (SRF). RNA and wh

NIAID Data Ecosystem50

Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase

Hedgehog信号通路

功能基因鉴定

To understand the molecular mechanisms underlying developmental abnormalities in Dyrk2-/- mice, we performed comprehensive whole-genome RNA sequencing of the MEFs from wild-type and Dyrk2-/- embryos

NIAID Data Ecosystem30

Combined constitutive canonical and non-canonical HH signaling caused by depletion of Patched 2 causes an MPN phenotype and transforms chronic MPNs into acute leukemias

Hedgehog信号通路

骨髓增殖性肿瘤转化机制

Combined constitutive canonical and non-canonical HH signaling caused by depletion of Patched 2 causes an MPN phenotype and transforms chronic MPNs into acute leukemias

ChEBI2016-01-11 更新60

Table_2_Sonic Hedgehog Is a Determinant of γδ T-Cell Differentiation in the Thymus.DOCX

γδT细胞分化

Hedgehog信号通路

Here we investigate the function of Hedgehog (Hh) signaling in thymic γδ T-cell maturation and subset differentiation. Analysis of Hh mutants showed that Hh signaling promotes γδ T-cell development in

NIAID Data Ecosystem30

Primary lung fibroblasts treated with hedgehog agonist, purmorphamine

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