HIV-CA Disulfide linked Hexamer bound to 4-Quinazolinone Scaffold inhibitor

HIV-CA Disulfide linked Hexamer bound to 4-Quinazolinone Scaffold inhibitor Descriptor: IODIDE ION, N-[(1S)-1-[(3P,7M)-3-{4-chloro-3-[(ethanesulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-7-(3-fluoro-4-formylphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]-2-(3,5-difluorophenyl)ethyl]-2-[3-(trifluoromethyl)-5,6-dihydrocyclopenta[c]pyrazol-1(4H)-yl]acetamide, Spacer peptide 1 Authors: Goldstone, D.C, Walsham, L. Deposit date: 2024-01-22 Release date: 2025-07-23 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of 4-Quinazolinone-Containing Phenylalanine Derivatives as Potent, Resistant-Tolerant HIV Capsid Inhibitors. MedComm (2020), 7, 2026