Enterococcus faecalis V19 NagY co-immunoprecipitation

Enterococcus faecalis is responsible for health-related pathologies. Under conditions of infection, the N-acetylglucosamine metabolism of E. faecalis undergoes significant changes in expression, even more important than those of virulence factors. This metabolism is mediated by the transcriptional antiterminator NagY. Combination of co-immunoprecipitation of NagY with RNA and a RNA-Seq approach was used to identify the regulon of this regulator. This study provides a valuable advance in the understanding of regulation and the importance of post-transcriptional actors in E. faecalis adaptation.