Stereoelectronic Tuning of Heteroaromatic γ‑Amino Acids for Turn Mimetic Design
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https://figshare.com/articles/dataset/Stereoelectronic_Tuning_of_Heteroaromatic_Amino_Acids_for_Turn_Mimetic_Design/29654346
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资源简介：
In this work, we developed two novel heterocyclic γ-amino
acids (Het-γAAs) based on thiazole and oxazole rings, preorganized
in a C7-turn reminiscent of the peptide
γ-turn in solution. Due to their role in stereoelectronic effects,
the heteroatoms in the heterocycle act as a molecular switch, allowing
control over conformations and stabilities of peptide turns.
创建时间：
2025-07-28
