Translesion DNA polymerases Rev1 and PolH promote LTR-retrotransposon transcription by safeguarding Pol II occupancy in both germline and somatic tissues of Drosophila
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP553319
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资源简介：
Through a genetic screen aimed to identify host factors for LTR-retrotransposons, we identified the pivotal role of two interacting translesion DNA polymerases, Rev1 and PolH. These associate with RNA Pol II, and facilitate Pol II occupancy at LTR-retrotransposons, thereby boosting LTR-retrotransposon transcription in both the germline and somatic tissue.
创建时间：
2025-09-28
