Sequencing of bacterial isolates from poultry

Chickens act as the host for many foodborne pathogens wherein the pathogen colonizes the GI tract and thereby leading to contamination of the carcass during slaughter and subsequent human infections. In the human gut, the pathogen attaches and invades the intestinal epithelium followed by toxin mediated cytopathy and enteritis. However, foodborne pathogens such as Salmonella and Campylobacter isolates naturally colonizes the poultry gut without effecting their health or production performance. These pathogens were capable of colonizing multiple hosts whilst competing with specialist microbiota in the gut. Comprehensive characterization of zoonotic bacterial isolates could facilitate in better understanding of their pathophysiology and development of effective intervention strategies.