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Critical Role of Sphingolipid Pathway Components in Murine Radiation-Induced Lung Injury: Protection by Sphingosine-1-Phosphate Analogues

ChEBI2010-11-17 更新2026-07-21 收录

放射性肺损伤机制

鞘脂通路药物干预

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-25295 数据链接链接失效反馈

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Critical Role of Sphingolipid Pathway Components in Murine Radiation-Induced Lung Injury: Protection by Sphingosine-1-Phosphate Analogues

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创建时间：

2010-11-17

放射性肺损伤机制

单细胞转录组学

Radiation-induced lung injury (RILI) is the most common complication associated with chest tumors, such as lung and breast cancers, after radiotherapy; however, the pathogenic mechanisms are unclear.H

NIAID Data Ecosystem100

Ionizing Radiation-induced Acute Damage in the Salivary Gland

放射性肺损伤机制

唾液转录组学

Ionizing radiation (IR) â induced salivary gland damage is a common adverse effect in radiotherapy for patients with head and neck cancers. Currently, there is no effective treatment for the resulti

NIAID Data Ecosystem70

Integrating metabolomics and transcriptomics reveals convergent pathways driving radiation-induced salivary gland dysfunction

放射性肺损伤机制

多组学整合分析

Purpose: The goal of this study is to integrate NGS-derived parotid salivary gland transcriptome profiling (RNA-seq) to metabolomics (UPLC-MS/MS) methods and identify mechanisms driving radiation-indu

NIAID Data Ecosystem60

Table_3_Exploring the Pharmacological Mechanism of Radix Salvia Miltiorrhizae in the Treatment of Radiation Pneumonia by Using Network Pharmacology.docx

中药网络药理学

放射性肺损伤机制

BackgroundRadiation pneumonia (RP) is the most common complication of radiotherapy to the thorax and seriously affects the survival rate and quality of life of patients. Radix Salviae Miltiorrhizae (R

NIAID Data Ecosystem80

Endothelial Shp2 deficiency controls alternative activation of macrophage preventing radiation-induced lung injury through Notch signaling

放射性肺损伤机制

Notch信号通路

Our findings demonstrate that endothelial Shp2 is a key regulator in radiation-induced lung injury by maintaining the radiation-induced Jag1 level through the β-catenin pathway, thereby reducing alter

NIAID Data Ecosystem60

Critical Role of Sphingolipid Pathway Components in Murine Radiation-Induced Lung Injury: Protection by Sphingosine-1-Phosphate Analogues

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