Clinical symptoms of subjects throughout the disease course.

Cognitive: cognitive decline, executive dysfunction, amnesia, agnosia, apraxia, alexia, language impairment, disorientation, and/or concentration impairment; Cerebellar: ataxia, nystagmus, and/or vertigo; Movement disorder: tremor, chorea, and/or extrapyramidal symptoms (does not include myoclonus); Visual: diplopia, oculomotor palsy, hemianopia, cortical blindness, visuospatial impairment, and/or visual hallucinations; Mood: depression, anxiety, mania, hypomania, emotional lability, and/or apathy; Psychosis: delusions, hallucinations, and/or psychosis not otherwise specified.