Crystal structure of Isocitrate dehydrogenase D252N mutant from Trypanosoma brucei in complexed with NADP+, alpha-ketoglutarate, and ca2+

Crystal structure of Isocitrate dehydrogenase D252N mutant from Trypanosoma brucei in complexed with NADP+, alpha-ketoglutarate, and ca2+ Descriptor: CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], ... Authors: Arai, N, Shiba, T, Inaoka, D.K, Kita, K, Wang, X, Otani, M, Matsushiro, S, Kojima, C. Deposit date: 2021-02-09 Release date: 2022-02-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of Isocitrate dehydrogenase from Trypanosoma brucei. To Be Published

本数据集为布氏锥虫（Trypanosoma brucei）来源的异柠檬酸脱氢酶D252N突变体与烟酰胺腺嘌呤二核苷酸磷酸（NADP+）、α-酮戊二酸及钙离子（Ca²+）形成复合物的晶体结构。配体信息：钙离子、异柠檬酸、NADP依赖性异柠檬酸脱氢酶等。作者：Arai N、Shiba T、Inaoka DK、Kita K、Wang X、Otani M、Matsushiro S、Kojima C。提交日期：2021-02-09，发布日期：2022-02-16，最后修改日期：2023-11-29。实验方法：X射线衍射（分辨率1.9埃）。引用文献：布氏锥虫异柠檬酸脱氢酶晶体结构，待发表。