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Transcription landscape of adipose tissue changes in response to telomerase knockout in mesenchymal progenitors

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP282041
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We generated mice with telomerase (TERT) gene knock-out (KO) that undergo premature telomere shortening in adipose stromal cells expressing Pdgfra or Pdgfrb. Stromal vascular cells were isolated from inguinal adipose tissue of Pdgfra-Cre; TERT fl/fl mice (Sample name A_SAT), Pdgfrb-Cre; TERT fl/fl mice (Sample name KO_SAT), and of control TERT WT mice (Sample name PBS_SAT). Overall design: scRNAseq analysis of subcutaneous adipose tissue stromal vascular cells was performed.
创建时间:
2020-12-30
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