Whole genome sequencing of Streptococcus pneumoniae
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https://www.ncbi.nlm.nih.gov/sra/SRP345305
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资源简介：
We performed whole-genome sequencing (WGS) for five pneumococcal clinical isolates belonging to serogroup 11. Aiming to disambiguate whether microbial glycoconjugates elicit a protective response from the lectin complement pathway, we demonstrate the human lectin ficolin-2 binds specific pneumococcal capsule structures, triggers complement-dependent opsonophagocytosis, and likely spurs the decreased invasiveness demonstrated by select pneumococcal non-vaccine serotypes.
创建时间：
2021-11-16
