Exploring Antibiotic Resistance in Diverse Homologs of the Dihydrofolate Reductase Protein Family through Broad Mutational Scanning
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https://figshare.com/articles/dataset/Exploring_Antibiotic_Resistance_in_Diverse_Homologs_of_the_Dihydrofolate_Reductase_Protein_Family_through_Broad_Mutational_Scanning/28266890/1
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资源简介：
This compressed zip file contains the of DHFR (variant-barcode) mapping and NGS barcode count files used in the RMD analysis scripts for the publication: <i>Exploring antibiotic resistance in diverse homologs of the dihydrofolate reductase protein family through broad mutational scanning</i>Karl J. Romanowicz et al. , Sci. Adv.11,eadw9178(2025). DOI:10.1126/sciadv.adw9178<br><br>The RMD analysis scripts are available here:<br>https://github.com/PlesaLab/DHFR<br><br>The folder structure within the zip file matches the RMD loading calls.<br>Additional links:<b>RPubs:</b> Rendered Code<b>NCBI BioProject:</b> PRJNA1189478 for raw .fastq files<br><br>FigShare Repository: Processed DHFR fitness scores.<br>
提供机构：
Hinton, Samuel; Plesa, Calin; Resnick, Carmen; Romanowicz, Karl
创建时间：
2025-01-23
