Crystal structure of human PIM1 kinase bound with CSH-4044 inhibitor

Crystal structure of human PIM1 kinase bound with CSH-4044 inhibitor Descriptor: (2,5-dihydroxy-4-methoxyphenyl)(6-hydroxy-5-methoxy-1,3-benzothiazol-2-yl)methanone, GLYCEROL, MAGNESIUM ION, ... Authors: Elkayam, E, Garg, A, Joshua-Tor, L. Deposit date: 2025-10-07 Release date: 2026-03-25 Last modified: 2026-04-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Identification and Validation of an Inhibitor of the Protein Kinases PIM and DYRK. J.Med.Chem., 69, 2026人类PIM1激酶与CSH-4044抑制剂结合的晶体结构。描述：(2,5-二羟基-4-甲氧基苯基)(6-羟基-5-甲氧基-1,3-苯并噻唑-2-基)甲酮、甘油、镁离子等。作者：Elkayam E、Garg A、Joshua-Tor L。提交日期：2025-10-07 发布日期：2026-03-25 最后修改日期：2026-04-22 实验方法：X射线衍射（1.95 Å）。引用：《蛋白激酶PIM与DYRK抑制剂的鉴定与验证》，载于《药物化学杂志（J.Med.Chem.）》，2026年，第69卷。