Mutational study of the EGFR monomer-dimer equilibrium at the JM domain phosphorylation sites.
收藏figshare.com2023-05-31 更新2025-01-21 收录
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a A and E stand for the phosphodeficient and phosphomimic mutation (alanine and glutamate substitution, respectively).b The state towards which the monomer-dimer equilibrium is shifted after EGF addition.c, d Minimum (Dmin) and maximum (Dmax) level of the diffusion coefficient.e Not determinable.Mutational study of the EGFR monomer-dimer equilibrium at the JM domain phosphorylation sites.
A与E分别代表磷缺乏型和磷模拟型突变（分别为丙氨酸和谷氨酸的替换）。b 描述了在EGF添加后，单体-二聚体平衡所趋向的状态。c, d 扩散系数的最小（Dmin）和最大（Dmax）水平。e 无法确定。对EGFR单体-二聚体平衡在JM域磷酸化位点处的突变进行研究。
提供机构：
PLOS ONE
