Human steroidogenic cytochrome P450 17A1 with 3alphaOH-5alpha-abiraterone analog
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5uys
下载链接
链接失效反馈官方服务：
资源简介：
Human steroidogenic cytochrome P450 17A1 with 3alphaOH-5alpha-abiraterone analog Descriptor: (3alpha,5alpha,8alpha)-17-(pyridin-3-yl)androst-16-en-3-ol, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase Authors: Scott, E.E, Petrunak, E.M. Deposit date: 2017-02-24 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.392 Å) Cite: Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
携带3α-羟基-5α-阿比特龙类似物的人类类固醇生成性细胞色素P450 17A1
描述符：(3α,5α,8α)-17-(吡啶-3-基)雄甾-16-烯-3-醇、含Fe的原卟啉IX、类固醇17α-羟化酶/17,20裂解酶
作者：Scott E.E.、Petrunak E.M.
提交日期：2017-02-24
发布日期：2018-02-28
最后修改日期：2023-10-04
实验方法：X射线衍射（分辨率2.392 Å）
引用：《携带前列腺癌药物阿比特龙代谢物的人类细胞色素P450 17A1结构揭示底物结合可塑性与第二结合位点》，《J. Biol. Chem.》，第299卷，2023年
创建时间：
2017-02-24
