Increasing evidence indicates that the cancer stem cell (CSC) subpopulation contributes to the therapeutic resistance and metastasis of tumors, leading to patient recurrence and death. Herein, we desi

Figshare2021-08-26 更新20

CRISPR library screening analysis on DMSO and Erlotinib 10ÂµM treated samples

三阴性乳腺癌耐药性

CRISPRi筛选

Triple-negative breast cancers (TNBCs) are the most aggressive subtype of breast cancer that have poor prognosis and very few treatment options. Although approximately 40-70% of TNBC patients have EGF

NIAID Data Ecosystem20

Impact of Mint3 on transcriptome in MDA-MB-231 tumors

三阴性乳腺癌耐药性

HIF1α信号通路

Owing to the lack of therapeutic targets, chemotherapy with cytotoxic drugs is the general treatment for triple-negative breast cancer (TNBC). However, most TNBCs acquire resistance to chemotherapy, t

NIAID Data Ecosystem20

Transcriptome analysis following mTORC1 inhibition by rapamycin in TNBC

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