Crystal Structure of the Klebsiella pneumoniae LpxH-lipid X complex

Crystal Structure of the Klebsiella pneumoniae LpxH-lipid X complex Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Cho, J, Zhou, P. Deposit date: 2019-06-25 Release date: 2020-02-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics. Proc.Natl.Acad.Sci.USA, 117, 2020

肺炎克雷伯菌（Klebsiella pneumoniae）LpxH-脂质X（lipid X）复合物的晶体结构 描述项：(R)-((2R,3S,4R,5R,6R)-3-羟基-2-(羟甲基)-5-((R)-3-羟基十四烷酰胺基)-6-(膦酰氧基)四氢-2H-吡喃-4-基)3-羟基十四烷酸酯、1,2-乙二醇、钙离子等。作者：Cho J、Zhou P。沉积日期：2019-06-25；发布日期：2020-02-12；最后修改日期：2023-10-11。实验方法：X射线衍射（1.92 Å）。引用文献：《磺酰哌嗪类抗生素抑制UDP-二酰基葡萄糖苷焦磷酸水解酶LpxH的结构基础》，《美国国家科学院院刊》，117卷，2020年。