Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG, alpha-1,2-mannobiose and hexatungstotellurate(VI) TEW

Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG, alpha-1,2-mannobiose and hexatungstotellurate(VI) TEW Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, 6-tungstotellurate(VI), ... Authors: Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. Deposit date: 2020-06-16 Release date: 2020-11-18 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020

人源内切-α-甘露糖苷酶MANEA的催化结构域与GlcIFG、α-1,2-甘露二糖及六碲钨酸盐(VI)（hexatungstotellurate(VI)，缩写TEW）形成的复合物结构。配体描述：4-(2-羟乙基)-1-哌嗪乙磺酸、5-羟甲基-3,4-二羟基哌啶、六碲钨酸盐(VI)等。作者：Sobala, L.F、Fernandes, P.Z、Hakki, Z、Thompson, A.J、Howe, J.D、Hill, M、Zitzmann, N、Davies, S、Stamataki, Z、Butters, T.D、Alonzi, D.S、Williams, S.J、Davies, G.J。提交日期：2020-06-16；发布日期：2020-11-18；最后修改日期：2024-01-24。实验方法：X射线衍射（分辨率1.8 Å）。引用文献：《人源内切-α-1,2-甘露糖苷酶（MANEA）——一种抗病毒宿主糖基化靶点的结构》，美国国家科学院院刊（Proc.Natl.Acad.Sci.USA），第117卷，2020年