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Supplemental Data for Review: "The Role and Mechanism of Hair Follicle Neural Crest Stem Cells and Their Exosomes in Repair of Peripheral Nerve Injury"

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Figshare2025-06-08 更新2026-04-08 收录
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https://figshare.com/articles/dataset/Supplemental_Data_for_Review_The_Role_and_Mechanism_of_Hair_Follicle_Neural_Crest_Stem_Cells_and_Their_Exosomes_in_Repair_of_Peripheral_Nerve_Injury_/29264159/1
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This dataset contains original supporting materials for the systematic review. It includes: <br>1. PRISMA Flow Diagram - Formats: SVG (editable vector) - Details: Documents literature screening process across PubMed and CNKI databases, with exclusion criteria and final inclusion count (n=46 studies). <br>2. Comparative Tables - Table 1: Characteristics of hfNCSCs and other stem cell types - Variables: Availability, Collection invasiveness, Differentiation potential, Secretome profiles - Data: CSV (machine-readable) - Table 2: Stem cell-derived exosomes for the treatment of PNI Models - Parameters: Exosome source, In vitro/vivo models, Key findings - Source: Direct extraction from manuscript with reference mapping [34-39] <br>3. Mechanism Figures - Figure 1: Cellular mechanisms of hair follicle neural crest stem cells (hfNCSCs) in peripheral nerve injury (PNI) repair (Direct differentiation + Paracrine modulation) - Figure 2: Multimodal actions of stem cell-derived exosomes in PNI regeneration (Axonal growth, Immunomodulation, ECM remodeling) <br>Utility: - Enables full reproducibility of literature analysis (PRISMA) - Provides mechanism visualizations for educational reuse (CC BY 4.0) - Serves as meta-analysis foundation for future studies <br>Relationship to Manuscript: Directly supports: - Section 2.1 (hfNCSCs biology) → Table 1 - Section 2.2 (hfNCSCs mechanisms) → Figure 1 - Section 3.2 (Exosome mechanisms) → Figure 2 &amp; Table 2 - Section 4 (hfNCSCs-Exos role) → Experimental data in Table 2 <br>Version: 1.0 (2025-06-05) License: CC Attribution 4.0 International
提供机构:
Zheng, Jiachen
创建时间:
2025-06-08
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