Three-Component Carboxylic Acid−Bipyridine Lattice Inclusion Host. Supramolecular Synthesis of Ternary Cocrystals

Cocrystallization of 1,3,5-cyclohexanetricarboxylic acid with 4,4‘-bipyridine bases of different CH2 chain
lengths (n = 0, 2, 4) has afforded the ternary host framework [H3CTA·bipy-eta(gauche)·(bipy-bu)0.5] (2), sustained by
O−H···N hydrogen bonds. Inclusion of p-dichlorobenzene in the square voids of host 2 provides the first example of a
quaternary cocrystal. Crystal structures of ternary cocrystals 1−3 show that methylene chains of bipy bases are not mere
inert spacer units but have a conformational and structural role in controlling the supramolecular architecture of molecular
complexes with carboxylic acids.