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Selective inhibition of RORgt-dependent Th17 differentiation but not thymocyte development by IMU-935

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NIAID Data Ecosystem2026-05-10 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP604120
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资源简介:
This study investigates transcriptomic and epigenetic changes in mouse CD4+ T cells under Th17 polarization conditions and treatment with IMU-935. RNA-seq and ChIP-seq (targeting RORgt) were performed to characterize transcriptional profiles and transcription factor binding patterns. The goal is to elucidate the molecular mechanisms underlying the drug response.
创建时间:
2026-01-11
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