Synthesis of Multisubstituted 1‑Naphthoic Acids via Ru-Catalyzed C–H Activation and Double-Alkyne Annulation under Air
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https://figshare.com/articles/dataset/Synthesis_of_Multisubstituted_1_Naphthoic_Acids_via_Ru-Catalyzed_C_H_Activation_and_Double-Alkyne_Annulation_under_Air/8321153
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资源简介：
An efficient [2 +
2 + 2] benzannulation of phthalic acids/anhydrides
with two alkynes was developed for synthesis of multisubstituted 1-naphthoic
acids via Ru-catalyzed C–H activation. The reaction preceded
well using atmospheric oxygen as the sole oxidant with high atom/step
economies. Facilitated by the free carboxyl group, the products can
be easily converted to diverse polycyclic molecules.
创建时间：
2019-06-13
