Maximum local reactogenicity.

*For each local reactogenicity outcome, a statistically significant difference was found among the three treatment arms (Kruskal-Wallis p ≤0.05; values not shown). Unadjusted P values specifically for 1010 PU vs. 1011 PU arms (shown in table) were subsequently calculated. None of these are significant after applying Simes procedure to control the false discovery rate at 0.05 to account for the multiple comparisons. **Mild: Pain/tenderness causing no or minimal limitation of use of limb; Moderate: pain/tenderness limiting use of limb or causing greater than minimal interference with usual social & functional activities; Severe: pain/tenderness causing inability to perform usual social & functional activities.