Expression Data from Osteoblasts with a cell-type specific Piezo1-deficiency or treated with Yoda 1
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE138159
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资源简介：
Piezo1 is a cellular mechanosensor that can be activated by the compound Yoda 1. Our aim was to evaluate the role of Piezo1 in skeletal metabolism. We investigated the effect of Yoda 1 or Runx2-Cre mediated Piezo1 deficiency on cultured primary murine calvarial osteoblasts. We used microarray analysis to detail the global gene expression of osteoblasts in response to Piezo1-stimulation and deficiency 3 sample sets with 3 independent repetitions for each sample set were compared. 1st sample set: Piezo1-floxed, Runx2-Cre negative cells treated with DMSO; 2nd sample set: Piezo1-floxed,Runx2-Cre negative cells treated with Yoda 1; 3rd sample set Piezo1-floxed,Runx2-Cre positive cells treated with DMSO
创建时间：
2021-02-17
